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Material number	Category	Name	Function	Intellectual property rights	Price	Order or Joint Research Request
University of the Ryukyus RM21-0007	Animal and Cell line from human (animal)	Rbm20 (S637A) knock-in mouse	Symbol: Rbm20em1Hide MGI ID: MGI:6437154 Allele Type: Endonuclease-mediated (Modified isoform(s)) Mutation: Single point mutation Mutation details: CRISPR/Cas9 technology generated a T to G nucleotide change resulting in a serine to alanine substitution at amino acid 637 (p.S637A). RT-PCR indicates the absence of the N2B isoform and expression of a giant N2BA isoform (N2BA-G) which includes exons 215-218, in homozygous hearts. The N2BA-type splicing predominates in the heterozygote but not the giant N2BA isoform. This mutation is equivalent to the S635A mutation reported in a sporadic case of dilated cardiomyopathy.	None	Academia: Cost of transaction Company: Negotiable
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