Fosb (F) allele produces only Fosb mRNA

Introduced nucleic acid: mouse Mth1 gene (7-kb EcoRI fragment containing exon 1 to 4) in which exon 3 was replaced with a pol II-neo-poly(A) cassette (Ref 1, 2). Characteristics of the Mth1-knockout mouse: lacking oxidized purine nucleoside triphosphatase, predisposed to spontaneous tumorigenesis in liver, stomach and lung (Ref 3). References 1. PNAS, 2001, 98(20):11456-11461. 2. Mol. Cell. Biol., 1993, 13, 2134-2140. 3. PNAS, 2001, 98(20):11456-11461. The heterozygous Mth1-KO mouse line has been maintained by backcrossing to C57BL6/J Jcl mouse line for 41 generations.

Phgdh-deficient mouse embryonic fibroblast transfected with mouse Phgdh cDNA

Phgdh-deficient mouse embryonic fibroblast

Phgdh-deficient mouse embryonic fibroblast transfected with Phgdh

the cell line has a function to absorb dsRNAs actively by integration of C. elegance membrane protein gene

soaking RNA interference and Bombyx mori nucleopolyhedrovirus (BmNPV) hypersensitive cell line

Anti-tumor, anti-aging, etc.

anti-tumor, anti-aging, etc